Novel Senecavirus A in Swine with Vesicular Disease, United States, July 2015

2014–2015 in Brazil, which were associated with idiopathic vesicular disease and neonatal death. Little diagnostic testing is performed on culled animals, which may in part explain the discrepancy between 1% of oral fluids submitted for diagnostic testing being positive for SVA (7), compared with 72% of culled swine swab specimen pools in this study . The sole sample from primary markets that was positive for SVA by qRT-PCR had a Ct of 36.9, just below the negative cutoff of 37. Further research is needed to address possible correlation between SVA and health status of animals sold at lower value to cull markets. A notable distinction between contemporary SVA in the United States and Brazil, however, is that all the US samples originated from healthy animals that showed no clinical symptoms. Given the high genetic similarity between contemporary US SVA sequences and those from Brazil, additional cofactors likely affect clinical disease.